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A UTI vaccine is a vaccine used for prevention of recurrent urinary tract infections (UTIs). [1] [2] A number of UTI vaccines have been developed and/or marketed.[1] [2] [3] These include Uromune (MV-140; sublingual spray), UroVaxom (OM-89, OM-8980; oral tablet), [4] Solco-Urovac (Strovac; vaginal suppository or intramuscular injection), [5] [6] ExPEC4V (V10, JNJ-63871860; intramuscular ...
[5] [6] [7] [2] However, in a 2024 study that was the first long-term study of Uromune, where 60% of individuals had a single course of Uromune and 40% had repeat courses 1 to 2 years after the first course, 54% of 89 women and men remained UTI-free 5 to 9 years after first receiving the vaccine. [17]
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TMP/SMX is commonly used due to its ability to achieve high concentrations in urinary tract tissues and urine. This antibiotic combination demonstrates notable efficacy in both the treatment and prophylaxis of recurrent urinary tract infections. [12] Common adverse effects include nausea, vomiting, rash,pruritus, and photosensitivity. [26]
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Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). [2] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. [ 2 ]
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder ( cystitis ) or urethra ( urethritis ) while upper urinary tract infections affect the kidney ( pyelonephritis ). [ 10 ]
Valaciclovir (Valtrex) [20] Herpes Simplex/Zoster Valganciclovir (Valcyte) [21] Cytomegalovirus (CMV) Vicriviroc: HIV-1: Schering-Plough pyrimidine CCR5 entry inhibitor Vidarabine: Herpes Simplex, Varicella Zoster: Zalcitabine: HIV Zanamivir (Relenza) [22] Influenza A, Influenza B Zidovudine: HIV [23] Antiretroviral
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