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Carcinoembryonic antigen (CEA) describes a set of highly-related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Consequently, CEA is usually present at very low levels in the blood of healthy adults (about 2–4 ng/mL). [2]
n/a Ensembl ENSG00000105388 n/a UniProt P06731 n/a RefSeq (mRNA) NM_001291484 NM_001308398 NM_004363 n/a RefSeq (protein) NP_001278413 NP_001295327 NP_004354 n/a Location (UCSC) Chr 19: 41.71 – 41.73 Mb n/a PubMed search n/a Wikidata View/Edit Human Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (C luster of D ifferentiation 66e), is a member of the ...
CA19-9 can be elevated in many types of gastrointestinal cancer, such as colorectal cancer, esophageal cancer and hepatocellular carcinoma. [1] Apart from cancer, elevated levels may occur in pancreatitis, cirrhosis, [1] and diseases of the bile ducts. [1] [3] It can also be elevated in people with obstruction of the bile ducts. [3]
No screening test is wholly specific, and a high level of tumor marker can still be found in benign tumors. The only tumor marker currently used in screening is PSA (prostate-specific antigen). Diagnostics; Tumor markers alone can't be used for diagnostic purposes, due to lack of sensitivity and specificity. [4]
Normally tyrosinase is produced in minute quantities but its levels are very much elevated in melanoma cells. Oncofetal antigens are another important class of tumor antigens. Examples are alphafetoprotein (AFP) and carcinoembryonic antigen (CEA). These proteins are normally produced in the early stages of embryonic development and disappear by ...
The objective of this study was to compare different tumor markers and their diagnostic value. The tumor markers tested in this experiment were CA 19-9, CA 242 and CEA tumor markers. The data revealed that although each marker have its own level of specificity and correspond to a cancer, all three makers together increase diagnostic value. [7]
n/a Ensembl ENSG00000086548 n/a UniProt P40199 n/a RefSeq (mRNA) NM_002483 n/a RefSeq (protein) NP_002474 n/a Location (UCSC) Chr 19: 41.75 – 41.77 Mb n/a PubMed search n/a Wikidata View/Edit Human Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (C luster of D ifferentiation 66c), is a member of the ...
The scientists discovered that gastric cancer tissues demonstrated high levels of CAMSAP2. The results positively correlated with tumor markers carcinoembryonic antigen and CA19-9. Bioinformatics analysis suggested CAMSAP2 is involved in epithelial-mesenchymal transition and the upregulation of TGF-β signaling.