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Ethylene oxide treatment is the most common chemical sterilization method, used for approximately 70% of total sterilizations, and for over 50% of all disposable medical devices. [ 26 ] [ 27 ] Ethylene oxide treatment is generally carried out between 30 and 60 °C (86 and 140 °F) with relative humidity above 30% and a gas concentration between ...
For example, medical device manufacturers design their sterilization processes for an extremely low SAL, such as 10 −6, which is a 1 in 1,000,000 chance of a non-sterile unit. SAL also describes the killing efficacy of a sterilization process. A very effective sterilization process has a very low SAL.
Ethylene oxide is a colorless gas at 25 °C (77 °F) and is a mobile liquid at 0 °C (32 °F) – viscosity of liquid ethylene oxide at 0 °C is about 5.5 times lower than that of water. The gas has a characteristic sweet odor of ether, noticeable when its concentration in air exceeds 500 ppm. [ 26 ]
Anprolene is a registered trade name for ethylene oxide that belongs to Andersen Sterilizers.. Harold Willids Andersen invented Anprolene in 1967 and used plastic bags and small ampoules, hence, substantially less ethylene oxide (EtO) than traditional chamber type sterilizers which employ tanks of EtO.
used in sterilization of heat-labile products like plastic or rubber syringes, catheters and gloves •X-ray source-do- •Infrared light source-do- •Ultraviolet light source-do- Inspissator: used to produce culture media for bacteriology that contain egg or serum, which coagulate on heating Tyndallizer
In microbiology, in the context of a sterilization procedure, the D-value or decimal reduction time (or decimal reduction dose) is the time (or dose of an antimicrobial drug) required, at a given condition (e.g. temperature) or set of conditions, to achieve a one-log reduction, that is, to kill 90% of relevant microorganisms. [1]
Sterilization of medical and pharmaceutical goods. [4] Nanotechnology is one of the fastest-growing new areas in science and engineering. Radiation is early applied tool in this area; arrangement of atoms and ions has been performed using ion or electron beams for many years. New applications concern nanocluster and nanocomposites synthesis. [5]
In organic chemistry, ethoxylation is a chemical reaction in which ethylene oxide (C 2 H 4 O) adds to a substrate. It is the most widely practiced alkoxylation, which involves the addition of epoxides to substrates. In the usual application, alcohols and phenols are converted into R(OC 2 H 4) n OH, where n ranges from 1 to 10. Such compounds ...