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Hexokinase-I (HK-I) is an enzyme activator because it draws glucose into the glycolysis pathway. Its function is to phosphorylate glucose releasing glucose-6-phosphate (G6P) as the product. HK-I not only signals the activation of glucose into glycolysis but also maintains a low glucose concentration to facilitate glucose diffusion into the cell.
Herbalife Nutrition products. Herbalife Nutrition's products include weight-loss and protein shakes, [37] as well as protein bars, teas, aloes, vitamins, and sports hydration, energy, and personal care products. [38] The company's original product is the Formula 1 protein shake, a soy-based meal-replacement shake. The product debuted in 1980 ...
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans is encoded by the TNFSF13B gene. [ 5 ] [ 6 ] BAFF is also known as B Lymphocyte Stimulator (BLyS) and TNF- and APOL-related leukocyte expressed ligand (TALL-1) and the Dendritic cell-derived ...
In February 1980, aged 24, Hughes founded Los Angeles-based Herbalife International. It has since become one of the world's largest distributors of Herbalife products through multi-level marketing, with sales of about $3.5 billion in 2007 and 2.1 million Independent Distributors. Now in 95 countries and achieving record retail sales of $7.5 ...
Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections. [1] AP-1 controls a number of cellular processes including differentiation, proliferation, and apoptosis. [2]
GM2A is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents them to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.
Johnson joined Herbalife Nutrition as CEO in 2003, and served as Chairman beginning in 2007. [9] [3]Johnson emphasized the need to pivot the Herbalife brand away from being exclusively concerned with weight-loss products and the broader perceptions associated with multi-level marketing, a view which he described in an interview with Fortune Magazine as, “When I took over in 2003, Herbalife ...