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  2. Dimethyl sulfoxide - Wikipedia

    en.wikipedia.org/wiki/Dimethyl_sulfoxide

    Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH 3) 2 S O.This colorless liquid is the sulfoxide most widely used commercially. It is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water.

  3. Dimethyl sulfoxide (data page) - Wikipedia

    en.wikipedia.org/wiki/Dimethyl_sulfoxide_(data_page)

    Phase behavior Triple point: 291.67 K (18.52 °C), ? Pa Critical point [2]: 720 K (447 °C), 5630 kPa Std enthalpy change of fusion, Δ fus H o: 14.37 kJ/mol Std entropy change

  4. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    DMSO is widely used as an alternative to water because it has a lower dielectric constant than water, and is less polar and so dissolves non-polar, hydrophobic substances more easily. It has a measurable pK a range of about 1 to 30. Acetonitrile is less basic than DMSO, and, so, in general, acids are weaker and bases are stronger in this solvent.

  5. Deuterated DMSO - Wikipedia

    en.wikipedia.org/wiki/Deuterated_DMSO

    Deuterated DMSO, also known as dimethyl sulfoxide-d 6, is an isotopologue of dimethyl sulfoxide (DMSO, (CH 3) 2 S=O)) with chemical formula ((CD 3) 2 S=O) in which the hydrogen atoms ("H") are replaced with their isotope deuterium ("D"). Deuterated DMSO is a common solvent used in NMR spectroscopy.

  6. Dimethyl sulfide - Wikipedia

    en.wikipedia.org/wiki/Dimethyl_sulfide

    Dimethyl sulfide (DMS) or methylthiomethane is an organosulfur compound with the formula (CH 3) 2 S.It is the simplest thioether and has a characteristic disagreeable odor. It is a flammable liquid that boils at 37 °C (99 °F).

  7. Partition coefficient - Wikipedia

    en.wikipedia.org/wiki/Partition_coefficient

    Likewise, it is used to calculate lipophilic efficiency in evaluating the quality of research compounds, where the efficiency for a compound is defined as its potency, via measured values of pIC 50 or pEC 50, minus its value of log P. [27] Drug permeability in brain capillaries (y axis) as a function of partition coefficient (x axis) [28]

  8. Dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Dissociation_constant

    The dissociation constant has molar units (M) and corresponds to the ligand concentration [] at which half of the proteins are occupied at equilibrium, [6] i.e., the concentration of ligand at which the concentration of protein with ligand bound [] equals the concentration of protein with no ligand bound []. The smaller the dissociation ...

  9. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    C A is the analytical concentration of the acid and C H is the concentration the hydrogen ion that has been added to the solution. The self-dissociation of water is ignored. A quantity in square brackets, [X], represents the concentration of the chemical substance X. It is understood that the symbol H + stands for the hydrated hydronium ion.