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The membrane attack complex (MAC) or terminal complement complex (TCC) is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is an effector of the immune system. Antibody -mediated complement activation leads to MAC deposition on the surface ...
Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor (" CR3 ") consisting of CD11b (integrin α M) and CD18 (integrin β 2). [1] The integrin α chain is noncovalently bound to the integrin β chain. It binds to iC3b and can be involved in cellular adhesion, binding to the intercellular adhesion ...
Complement-dependent cytotoxicity (CDC) is an effector function of IgG and IgM antibodies.When they are bound to surface antigen on target cell (e.g. bacterial or viral infected cell), the classical complement pathway is triggered by bonding protein C1q to these antibodies, resulting in formation of a membrane attack complex (MAC) and target cell lysis.
Complement component 9. Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. [5] Once activated, about 12-18 molecules of C9 polymerize to form pores in target cell membranes, causing lysis and cell death. [6] C9 is one member of the complement membrane attack complex (MAC ...
In 2014, Duda programmed, created and released Serum, a VST plugin to be used by DJs and producers in the electronic dance music scene. [9] Its GUI was designed by Lance Thackeray. [10] Serum later won multiple awards. [5] In 2016, Xfer partnered with Splice and announced a "rent-to-own" plan for Serum, allowing producers to own the plugin at a ...
Anti-aging product. Anti-aging creams are predominantly moisturizer -based skin care products marketed with unproven claims of making the consumer look younger by reducing, masking or preventing signs of skin aging. Anti-aging supplements are ingestible products promoted to diminish the effects of aging, including vitamin supplements, powders ...
Biology and pharmacology. Serum (blood), plasma from which the clotting proteins have been removed. Antiserum, blood serum with specific antibodies for passive immunity. Serous fluid, any clear bodily fluid.
Complement control protein. Complement control proteins are proteins that interact with components of the complement system. The complement system is tightly regulated by a network of proteins known as "regulators of complement activation (RCA)" that help distinguish target cells as "self" or "non-self." A subset of this family of proteins ...