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Enthesitis is inflammation of the entheses (singular: enthesis), the sites where tendons, ligaments and joint capsules attach to bones. [1] [2] It is a type of enthesopathy, meaning any pathologic condition of the entheses, with or without inflammation. There are some cases of isolated, primary enthesitis which are very poorly studied and ...
Juvenile idiopathic arthritis (JIA), formerly known as juvenile rheumatoid arthritis (JRA), [1] is the most common chronic rheumatic disease of childhood, affecting approximately 3.8 to 400 out of 100,000 children. [3]
[2] [3] In a fibrous enthesis, the collagenous tendon or ligament directly attaches to the bone. In a fibrocartilaginous enthesis, the interface presents a gradient that crosses four transition zones: [4] Tendinous area displaying longitudinally oriented fibroblasts and a parallel arrangement of collagen fibres
The development of targeted biological treatments has had an impact on enteropathic arthritis management. Psoriatic arthritis , [ 32 ] [ 33 ] enthesopathy linked to spondyloarthropathy , [ 34 ] and refractory ankylosing spondylitis [ 35 ] can all benefit from biological blockade using the TNFa antagonists etanercept and infliximab .
Between 8 and 12 months of age, the digestive system improves, and many babies begin eating finger foods. Their diet is still limited, however, because most babies lack molars or canines at this age, and often have a limited number of incisors. By 18 months, babies often have enough teeth and a sufficiently mature digestive system to eat the ...
Tendinopathy is a type of tendon disorder that results in pain, swelling, and impaired function. [2] The pain is typically worse with movement. [2] It most commonly occurs around the shoulder (rotator cuff tendinitis, biceps tendinitis), elbow (tennis elbow, golfer's elbow), wrist, hip, knee (jumper's knee, popliteus tendinopathy), or ankle (Achilles tendinitis).
An eating disorder is a mental disorder that interferes with normal food consumption. It is defined by abnormal eating habits, and thoughts about food that may involve eating much more or much less than needed. [13] Common eating disorders include anorexia nervosa, bulimia nervosa, and binge-eating disorder. [14]
Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...