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Lisinopril/amlodipine is a combination of two agents which both act to induce vascular smooth muscle relaxation to lower blood pressure in distinct ways: [1]. Lisinopril inhibits angiotensin converting enzyme (ACE), the enzyme responsible for converting angiotensin I into angiotensin II (a vasoconstrictor).
The metabolism of metoprolol can vary widely among patients, often as a result of hepatic impairment [9] or CYP2D6 polymorphism. [10] Metoprolol was first made in 1969, patented in 1970, and approved for medical use in 1978. [11] [12] [13] It is on the World Health Organization's List of Essential Medicines. [14] It is available as a generic ...
A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. [1] [2] Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug is absorbed, distributed, metabolized, and excreted . [3] [4]
The term "me-too drug" or "follow-on drug" refers to a medication that is similar to a pre-existing drug, usually by making minor modifications to the prototype, reflected in slight changes in the profiles of side effects or activity, and used to treat conditions for which drugs already exist.
In accordance with the pharmacological effects, commonly prescribed drugs can be divided into different groups. Drugs in the same group exert nearly identical effects, and can be utilized for treating the prevailing disease and sometimes, preventing complications of the existing diseases. The use of commonly prescribed drugs can be reflected ...
Cardiovascular agents are drugs used to treat diseases associated with the heart or blood vessels. These medications are available for purchase only with a physician’s prescription . They include, but are not limited to, drugs that target hypertension ( antihypertensives ), hyperlipidemia ( antihyperlipidemics ) and blood clotting (blood ...
Ximelagatran (Exanta or Exarta, H 376/95) is an anticoagulant that has been investigated extensively as a replacement for warfarin [1] that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy.
Nadolol is used to treat hypertension and for long-term treatment of angina pectoris and is approved by the FDA for these purposes. [8]It is regularly used off-label [8] for control of heart rate in people with atrial fibrillation, [9] prevention of migraine headaches; [10] prevention of bleeding veins in people with portal hypertension caused by cirrhosis; [4] and to treat people with high ...
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related to: what drug can replace metoprolol- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
