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  2. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    Proton-pump inhibitors are named using the suffix "-prazole". There is a purported correlation (but no proven causal link) between the use of PPIs and the risk of dementia. [ 6 ] However, this remain controversial as chronic and co-morbid pathology, and resultant polypharmacy (including increased consumption of PPIs), will probably itself also ...

  3. Helicobacter pylori eradication protocols - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori...

    Helicobacter pylori eradication protocols is a standard name for all treatment protocols for peptic ulcers and gastritis in the presence of Helicobacter pylori infection. The primary goal of the treatment is not only temporary relief of symptoms but also total elimination of H. pylori infection.

  4. Famotidine - Wikipedia

    en.wikipedia.org/wiki/Famotidine

    Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4] It begins working within ...

  5. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Stress gastritis and ulcer prevention in critical care [18] Gastrinomas; Zollinger–Ellison syndrome (often 2–3× the regular dose is required) [19] Specialty professional organizations recommend that people take the lowest effective PPI dose to achieve the desired therapeutic result when used to treat gastroesophageal reflux disease long-term.

  6. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    H 2 antagonists can be used in the treatment of dyspepsia, peptic ulcers and gastroesophageal reflux disease. They have been surpassed by proton pump inhibitors (PPIs). The PPI omeprazole was found to be more effective at both healing and alleviating symptoms of ulcers and reflux oesophagitis than the H 2 blockers ranitidine and cimetidine. [2]

  7. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H + /K + ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (GERD) and peptic ulcer disease. PPIs also can bind to other types of proton pumps such as those ...

  8. Gastroesophageal reflux disease - Wikipedia

    en.wikipedia.org/wiki/Gastroesophageal_reflux...

    The primary medications used for GERD are proton-pump inhibitors, H 2 receptor blockers and antacids with or without alginic acid. [9] The use of acid suppression therapy is a common response to GERD symptoms and many people get more of this kind of treatment than their case merits.

  9. Linaprazan - Wikipedia

    en.wikipedia.org/wiki/Linaprazan

    Linaprazan is an experimental drug for the treatment of gastroesophageal reflux disease (GERD). Unlike the proton-pump inhibitors (PPIs) which are typically used to treat GERD, linaprazan is a potassium-competitive acid blocker (P-CAB). [1] [2] Linaprazan was developed by AstraZeneca, but it was not successful in clinical trials. [3]

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