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A proton pump is an integral membrane protein pump that builds up a proton gradient across a biological ... This enzyme functions as the proton pump of the stomach, ...
The gastric hydrogen potassium ATPase or H + /K + ATPase is the proton pump of the stomach.It exchanges potassium from the intestinal lumen with cytoplasmic hydronium [2] and is the enzyme primarily responsible for the acidification of the stomach contents and the activation of the digestive enzyme pepsin [3] (see gastric acid).
Amino acids and sugars are taken up from sea water in the presence of extracellular sodium and is driven by the NA + /K +-ATPase pump. [ 1 ] In the roots of plants , the H+/K+ symporters are only one member of a group of several symporters/antiporters that specifically allow only one charged hydrogen ion (more commonly known as a proton) and ...
V-ATPases couple the energy of ATP hydrolysis to proton transport across intracellular and plasma membranes of eukaryotic cells. It is generally seen as the polar opposite of ATP synthase because ATP synthase is a proton channel that uses the energy from a proton gradient to produce ATP. V-ATPase however, is a proton pump that uses the energy ...
-ATPase or proton pump creates the electrochemical gradients in the plasma membrane of plants, fungi, protists, and many prokaryotes. Here, proton gradients are used to drive secondary transport processes. As such, it is essential for the uptake of most metabolites, and also for plant responses to the environment (e.g., movement of leaves).
The proton pump is the terminal stage in gastric acid secretion, being directly responsible for secreting H + ions into the gastric lumen, making it an ideal target for inhibiting acid secretion. [ citation needed ] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective than receptor ...
Proton ATPase, graphic representation. In the field of enzymology, a proton ATPase, or H +-ATPase, is an enzyme that catalyzes the following chemical reaction: ATP + H 2 O + H + in ADP + phosphate + H + out. The 3 substrates of this enzyme are ATP, H 2 O, and H +, whereas its 3 products are ADP, phosphate, and H +.
Gastric parietal cells, osteoclasts, and other acid-secreting cells have chloride-bicarbonate antiporters that function in the basolateral membrane to dispose of excess bicarbonate left behind by the function of carbonic anhydrase and apical proton pumps. However, base-secreting cells exhibit apical chloride-bicarbonate exchange and basolateral ...