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Structures with names 4- and 5-nitroimidazole are equivalent from the perspective of drugs since these tautomers readily interconvert. Drugs of the 5-nitro variety include metronidazole, tinidazole, nimorazole, dimetridazole, pretomanid, ornidazole, megazol, and azanidazole. Drugs based on 2-nitroimidazoles include benznidazole and azomycin. [3]
2-Methylimidazole (1) may be prepared via the Debus-Radziszewski imidazole synthesis, or from ethylenediamine and acetic acid, followed by treatment with lime, then Raney nickel. 2-Methylimidazole is nitrated to give 2-methyl-4(5)-nitroimidazole (2), which is in turn alkylated with ethylene oxide or 2-chloroethanol to give metronidazole (3 ...
2-Methylimidazole is an organic compound that is structurally related to imidazole with the chemical formula CH 3 C 3 H 2 N 2 H. It is a white or colorless solid that is highly soluble in polar organic solvents and water. It is a precursor to a range of drugs and is a ligand in coordination chemistry.
IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as [1] This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.
1-Methylimidazole or N-methylimidazole is an aromatic heterocyclic organic compound with the formula CH 3 C 3 H 3 N 2. It is a colourless liquid that is used as a specialty solvent, a base, and as a precursor to some ionic liquids.
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2-Methylimidazole; 4-Methylimidazole, which is chemically distinct from, but readily interconvertable with 5-methylimidazole This page was last edited on 27 February ...
New data on animal euthanasia further shows the strain inside the animal shelter, where officials have been raising alarms for months.
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