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Serotonin is a neurotransmitter involved in multiple complex biological processes including aggression, pain, sleep, appetite, anxiety, depression, migraine, and vomiting. [10] In humans the effects of excess serotonin were first noted in 1960 in patients receiving an MAOI and tryptophan. [54] The syndrome is caused by increased serotonin in ...
Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
An increase in dopamine in the caudate and putamen have been found in binge eaters, [47] and studies have found a decrease in a particular serotonin transporter (5-HT) in binge eaters compared to controls. [48] Both the caudate nucleus and putamen make up the dorsal striatum and are important as part of the brain's memory system. Dopamine is ...
Its inhibitory effects on serotonin reuptake and 5-HT 2C receptors are comparatively weak. [122] In relation to these properties, trazodone does not have similar properties to selective serotonin reuptake inhibitors (SSRIs) [122] and is not particularly associated with increased appetite and weight gain – unlike other 5-HT 2C antagonists like ...
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the ...
Other Conditions That Can Cause Appetite Loss. Sudden and major changes in your appetite, eating habits, and weight can also be symptoms of depression — a common mood disorder that shares many ...
This meta-analysis found that loneliness is associated with a 31% increase in dementia. One of the best things you can do to prevent loneliness is to nurture strong, healthy relationships. If you ...
A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft. A selective serotonin releasing agent (SSRA) is an SRA with less significant or no efficacy in producing neurotransmitter efflux at other types of monoamine neurons, including dopamine and norepinephrine neurons. [1]
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