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Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1] It is taken by mouth. [1] It was approved for medical use in the United States in 2006. [1]
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
The American College of Chest Physicians emphasizes that cough medicines are not designed to treat whooping cough, a cough that is caused by bacteria and can last for months. [8] No over-the-counter cough medicines have been found to be effective in cases of pneumonia. [9] They are not recommended in those who have COPD, chronic bronchitis, or ...
A dry cough, on the other hand, is commonly associated with irritated or inflamed upper airways, says Glen B. Chun, M.D., an assistant professor of medicine and clinical director of Mount Sinai's ...
Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug and entheogen for its dissociative effects. [1] Street names include Brownies , Dextro , Drix , Gel , Groove , Lean , Mega-perls , Poor man's ecstasy , Poor man's PCP, Red devils , Robo , Rojo ...
The lozenges are sugar-free too, a good element in a cough drop, says Richard Watkins, M.D., an infectious disease physician and professor of internal medicine at the Northeast Ohio Medical ...
The cough syrup codeine linctus will now only be available to patients with a prescription due to concerns over abuse and addiction. The medicine, which was previously available to buy in ...
One mucoactive agent, guaifenesin, has anxiolytic and muscle-relaxing properties. It is commonly available in cough syrups and also as sustained-release tablets. Mucolytics can dissolve thick mucus and are usually used to help relieve respiratory difficulties. They do this by breaking down the chemical bonds between molecules in the mucus. [5]
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