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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Cialis Drug Interactions. Tadalafil side effects aren’t the only concern when taking this drug. As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications ...

  3. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Medications and foods may cause problems with ED medication and intensify the effects of tadalafil. Beyond potential drug interactions, this also means that you shouldn’t double up on a missed dose.

  4. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    [19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...

  5. What Is the Safest ED Medication? - AOL

    www.aol.com/safest-ed-medication-105700669.html

    Tadalafil. The active ingredient in Cialis, tadalafil is a long-lasting medication that can provide relief from ED for up to 36 hours. Vardenafil. The active ingredient in Levitra, vardenafil ...

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]

  7. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [ 5 ] [ 6 ] [ 8 ] It is taken by mouth . [ 8 ]

  8. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Tadalafil. The active ingredient in Cialis, tadalafil is a long-lasting medication that can provide relief from ED for up to 36 hours. Vardenafil. The active ingredient in Levitra, vardenafil can ...

  9. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

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