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Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
Programmed cell death (PCD; sometimes referred to as cellular suicide [1]) is the death of a cell as a result of events inside of a cell, such as apoptosis or autophagy. [2] [3] PCD is carried out in a biological process, which usually confers advantage during an organism's lifecycle.
John Foxton Ross Kerr AO (24 January 1934 – 4 June 2024) was an Australian pathologist.He was the first to describe the ultrastructural changes in apoptosis, and could show that they differ significantly from the changes that occur in necrosis, another form of cell death.
William Robert Grove c. 1850. In 1846, Grove published On The Correlation of Physical Forces [15] [16] in which he anticipated the general theory of the conservation of energy that was more famously put forward in Hermann von Helmholtz' Über die Erhaltung der Kraft (On the Conservation of Force) published the following year. [7]
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