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  2. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Any antiretroviral drug: Black tar heroin: Whoonga, Nyaope [8] Widespread use in South Africa. Whoonga is classically reputed to be a combination of heroin with antiretroviral drugs such as ritonavir and/or efavirenz, often combined with additional drugs such as cannabis or hashish, methamphetamine and/or methaqualone: Any deliriant or diphen ...

  3. Evolutionary models of human drug use - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_models_of...

    The neurotoxin regulation model of human drug use proposes that during the course of human evolution, plant consumption played a key role. The hypothesis suggests that the compulsory consumption of both the nutrients and neurotoxins in plants selected for a system capable of maximizing the benefits of plant energy extraction while mitigating ...

  4. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage.

  5. List of cocaine analogues - Wikipedia

    en.wikipedia.org/wiki/List_of_cocaine_analogues

    This is a list of cocaine analogues.A cocaine analogue is an (usually) artificial construct of a novel chemical compound from (often the starting point of natural) cocaine's molecular structure, with the result product sufficiently similar to cocaine to display similarity in, but alteration to, its chemical function.

  6. List of antiviral drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_antiviral_drugs

    List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 ...

  7. De-linkage - Wikipedia

    en.wikipedia.org/wiki/De-linkage

    De-linkage is a proposed model for development of new pharmaceutical drugs [1] where "de-link" refers to isolating the profitability of a drug from its volume of sales. [2]In the current business model, the pharmaceutical industry relies on the pricing and sales of its products to generate profits and to finance research and development of new drugs.

  8. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Misoprostol is approved for medical abortion regimens when administered at the office, but clinicians often give abortion patients the drug to be taken at home. [ 15 ] Modafinil is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy , shift work sleep disorder , and obstructive sleep apnea .

  9. Background selection - Wikipedia

    en.wikipedia.org/wiki/Background_selection

    Background selection describes the loss of genetic diversity at a locus due to negative selection against deleterious alleles with which it is in linkage disequilibrium. [1] The name emphasizes the fact that the genetic background, or genomic environment, of a mutation has a significant impact on whether it will be preserved versus lost from a population.