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Increased oxygen consumption during sustained exercise reduces the oxygen saturation of venous blood, which can reach less than 15% in a trained athlete; although breathing rate and blood flow increase to compensate, oxygen saturation in arterial blood can drop to 95% or less under these conditions. [28]
Diabetes mellitus, also known as type II diabetes, is a disease that affects over three million people in the U.S. per year. This disease affects the glucose levels in the body by causing them to rise higher than normal. In type II diabetic patients, the body develops insulin resistance that initiates an increase in blood glucose levels. [1]
The needs of the body's blood oxygen may fluctuate such as during exercise when more oxygen is required [5] or when living at higher altitudes. A blood cell is said to be "saturated" when carrying a normal amount of oxygen. [6] Both too high and too low levels can have adverse effects on the body. [7]
Hypoxia can be due to external causes, when the breathing gas is hypoxic, or internal causes, such as reduced effectiveness of gas transfer in the lungs, reduced capacity of the blood to carry oxygen, compromised general or local perfusion, or inability of the affected tissues to extract oxygen from, or metabolically process, an adequate supply ...
Hypoxemia is usually defined in terms of reduced partial pressure of oxygen (mm Hg) in arterial blood, but also in terms of reduced content of oxygen (ml oxygen per dl blood) or percentage saturation of hemoglobin (the oxygen-binding protein within red blood cells) with oxygen, which is either found singly or in combination. [2] [5]
Cardiovascular fitness can be assessed through various methods, including maximal oxygen uptake (V̇O 2max), which is the maximal amount of oxygen that can be used during exercise. Biomarkers , such as those used for assessing blood lipids , inflammation , glucose tolerance , and hemostasis , may be used to monitor progress during the ...
Venous blood with an oxygen concentration of 15 mL/100 mL would therefore lead to typical values of the a-vO 2 diff at rest of around 5 mL/100 mL. During intense exercise, however, the a-vO 2 diff can increase to as much as 16 mL/100 mL due to the working muscles extracting far more oxygen from the blood than they do at rest. [citation needed]
Exercise for diabetes: Exercise is a particularly potent tool for glucose control in those who have diabetes mellitus. In a situation of elevated blood glucose (hyperglycemia), moderate exercise can induce greater glucose disposal than appearance, thereby decreasing total plasma glucose concentrations. As stated above, the mechanism for this ...