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Negligible senescence is a term coined by biogerontologist Caleb Finch to denote organisms that do not exhibit evidence of biological aging , such as measurable reductions in their reproductive capability, measurable functional decline, or rising death rates with age. [1]
Biological immortality (sometimes referred to as bio-indefinite mortality) is a state in which the rate of mortality from senescence (or aging) is stable or decreasing, thus decoupling it from chronological age. Various unicellular and multicellular species, including some vertebrates, achieve this state either throughout their existence or ...
The term "negligible senescence" was first used in the early 1990s by professor Caleb Finch to describe organisms such as lobsters and hydras, which do not show symptoms of aging. The term "engineered negligible senescence" first appeared in print in Aubrey de Grey's 1999 book The Mitochondrial Free Radical Theory of Aging. [8]
Senescence can be induced by several factors, including telomere shortening, [37] DNA damage [38] and stress. Since the immune system is programmed to seek out and eliminate senescent cells, [39] it might be that senescence is one way for the body to rid itself of cells damaged beyond repair. The links between cell senescence and aging are several:
A “Wings of Fire” animated series based on the books of the same name is in development at Amazon MGM Studios, Variety has learned exclusively. Fans of the books by author Tui T. Sutherland ...
Wings of Fire is a series of fantasy novels about dragons, written by Tui T. Sutherland and published by Scholastic Inc. [1] The series has been translated into over ten languages, [ 2 ] has sold over 14 million copies, and has been on the New York Times bestseller list for over 200 weeks.
Strategies for Engineered Negligible Senescence: Why Genuine Control of Aging May Be Foreseeable. Annals of the New York Academy of Sciences. ISBN 978-1573314961. de Grey, Aubrey; Rae, Michael (2007). Ending Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in Our Lifetime. New York: St. Martin's Press. ISBN 978-0-312-36706-0.
The poetic and captivating coming-of-age … Talent-driven doc sales outfit Rise & Shine has boarded “Fire Fire Fire” (“Feu Feu Feu”), the feature debut of Swiss rising voice Pauline ...