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Cramps are common and tend to occur at rest, usually at night (nocturnal leg cramps). [2] [5] They are also often associated with pregnancy, physical exercise or overexertion, and age (common in older adults); in such cases, cramps are called idiopathic, because there is no underlying pathology.
Hypokalemia which is recurrent or resistant to treatment may be amenable to a potassium-sparing diuretic, such as amiloride, triamterene, spironolactone, or eplerenone. Concomitant hypomagnesemia will inhibit potassium replacement, as magnesium is a cofactor for potassium uptake.
Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. [1] It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...
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Active and inactive μ-opioid receptors [1] Image of visual pain. Pain management is an aspect of medicine and health care involving relief of pain (pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging.
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