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Transketolase (abbreviated as TK) is an enzyme that, in humans, is encoded by the TKT gene. [1] It participates in both the pentose phosphate pathway in all organisms and the Calvin cycle of photosynthesis. Transketolase catalyzes two important reactions, which operate in opposite directions in these two pathways.
Transketolase-like-1 (TKTL1) is a gene closely related to the transketolase gene (TKT). It emerged in mammals during the course of evolution and, according to the latest research findings, is considered one of the key genes that distinguishes modern humans ( Homo sapiens ) from Neanderthals .
In what is essentially the reverse of step two, the electrons push back in the opposite direction forming a new bond between the substrate carbon and another atom. (In the case of the decarboxylases, this creates a new carbon-hydrogen bond. In the case of transketolase, this attacks a new substrate molecule to form a new carbon-carbon bond.)
74419 Ensembl ENSG00000151005 ENSMUSG00000025519 UniProt Q9H0I9 Q9D4D4 RefSeq (mRNA) NM_032136 NM_001271574 NM_028927 RefSeq (protein) NP_115512 NP_001258503 NP_083203 Location (UCSC) Chr 4: 163.47 – 163.47 Mb Chr 8: 66.96 – 66.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transketolase-like protein 2 is an enzyme that in humans is encoded by the TKTL2 gene. References ^ a b ...
Dehydrogenase E1 and transketolase domain containing 1 is a protein that in humans is encoded by the DHTKD1 gene. This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids , including lysine .
transketolase and transaldolase: aldehyde or ketone groups EC 2.3: acyltransferase: acyl groups or groups that become alkyl groups during transfer EC 2.4: glycosyltransferase, hexosyltransferase, and pentosyltransferase: glycosyl groups, as well as hexoses and pentoses: EC 2.5: riboflavin synthase and chlorophyll synthase: alkyl or aryl groups ...
Ribose 5-phosphate (R5P) is both a product and an intermediate of the pentose phosphate pathway.The last step of the oxidative reactions in the pentose phosphate pathway is the production of ribulose 5-phosphate.
Sedoheptulose 7-phosphate is an intermediate in the pentose phosphate pathway. [1]It is formed by transketolase and acted upon by transaldolase.. Sedoheptulokinase is an enzyme that uses sedoheptulose and ATP to produce ADP and sedoheptulose 7-phosphate.