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The sample odds ratio n 11 n 00 / n 10 n 01 is easy to calculate, and for moderate and large samples performs well as an estimator of the population odds ratio. When one or more of the cells in the contingency table can have a small value, the sample odds ratio can be biased and exhibit high variance .
The confidence interval can be expressed in terms of statistical significance, e.g.: "The 95% confidence interval represents values that are not statistically significantly different from the point estimate at the .05 level." [20] Interpretation of the 95% confidence interval in terms of statistical significance.
The Clopper–Pearson interval is an early and very common method for calculating binomial confidence intervals. [11] This is often called an 'exact' method, as it attains the nominal coverage level in an exact sense, meaning that the coverage level is never less than the nominal 1 − α . {\displaystyle \ 1-\alpha ~.} [ 2 ]
However, at 95% confidence, Q = 0.455 < 0.466 = Q table 0.167 is not considered an outlier. McBane [ 1 ] notes: Dixon provided related tests intended to search for more than one outlier, but they are much less frequently used than the r 10 or Q version that is intended to eliminate a single outlier.
If each interval individually has coverage probability 0.95, the simultaneous coverage probability is generally less than 0.95. A 95% simultaneous confidence band is a collection of confidence intervals for all values x in the domain of f(x) that is constructed to have simultaneous coverage probability 0.95.
By symmetry, for only successes, the 95% confidence interval is [1−3/ n,1]. The rule is useful in the interpretation of clinical trials generally, particularly in phase II and phase III where often there are limitations in duration or statistical power. The rule of three applies well beyond medical research, to any trial done n times. If 300 ...
a) The expression inside the square root has to be positive, or else the resulting interval will be imaginary. b) When g is very close to 1, the confidence interval is infinite. c) When g is greater than 1, the overall divisor outside the square brackets is negative and the confidence interval is exclusive.
Classically, a confidence distribution is defined by inverting the upper limits of a series of lower-sided confidence intervals. [15] [16] [page needed] In particular, For every α in (0, 1), let (−∞, ξ n (α)] be a 100α% lower-side confidence interval for θ, where ξ n (α) = ξ n (X n,α) is continuous and increasing in α for each sample X n.