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Lactase (EC 3.2.1.108) is an enzyme produced by many organisms and is essential to the complete digestion of whole milk. It breaks down the sugar lactose into its component parts, galactose and glucose. Lactase is found in the brush border of the small intestine of humans and other mammals.
Many adult humans lack the lactase enzyme, which has the same function as β-galactosidase, so they are not able to properly digest dairy products. β-Galactose is used in such dairy products as yogurt, sour cream, and some cheeses which are treated with the enzyme to break down any lactose before human consumption. In recent years, β ...
The lactase enzyme has two active sites which break down lactose. The first is at Glu1273 and the second is at Glu1749, which separately break down lactose into two separate kinds of molecules. [1] At least six mutations (single-nucleotide polymorphisms – SNPs) have been associated with lactase expression. [28]
Lactose intolerance does not cause damage to the gastrointestinal tract. [2] Lactose intolerance is due to the lack of the enzyme lactase in the small intestines to break lactose down into glucose and galactose. [3] There are four types: primary, secondary, developmental, and congenital. [1]
Lactose-free milk is cow’s milk that has had lactase—an enzyme that breaks down (i.e., digests) lactose—added to effectively eliminate the lactose content.
Some companies take the additional step of adding lactase, an enzyme that breaks down lactose, to eliminate even more of the milk sugar in the product. (Check the label for lactose information ...
Lactose, or milk sugar, is a disaccharide composed of galactose and glucose and has the molecular formula C 12 H 22 O 11.Lactose makes up around 2–8% of milk (by mass). The name comes from lact (gen. lactis), the Latin word for milk, plus the suffix -ose used to name sugars.
Lactase (breaks down lactose into glucose and galactose) Maltase (breaks down maltose into 2 glucoses) Sucrase (breaks down sucrose into glucose and fructose) Trehalase (breaks down trehalose into 2 glucoses) For a thorough scientific overview of small-intestinal disaccharidases, one can consult chapter 75 of OMMBID. [1]
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