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Mirabegron, sold under the brand name Myrbetriq among others, is a medication used to treat overactive bladder. [5] Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine. [6] It is taken by mouth. [5] Common side effects include high blood pressure, headaches, and urinary tract infections. [5]
The chemical structure of Solabegron, a β 3-adrenergic receptor agonist. Mirabegron is a selective β 3-AR agonist that affects the detrusor muscles of the urinary bladder.By stimulation of β 3-AR the contraction of the smooth muscles of the bladder is decreased and the bladder can store more volume of urine at a given time.
Oxybutynin, sold under the brand name Ditropan among others, is an anticholinergic medication primarily used to treat overactive bladder. It is widely considered a first-line therapy for overactive bladder due to its well-studied side effect profile, broad applicability, and continued efficacy over long periods of time.
Overactive bladder (OAB) is a common condition where there is a frequent feeling of needing to urinate to a degree that it negatively affects a person's life. [2] The frequent need to urinate may occur during the day, at night, or both. [4]
Oxybutynin: M1/3/4 selective overactive bladder; urge incontinence; Ditropan Pirenzepine: M1-selective [5] in peptic ulcer (not much anymore) [5] (fewer than non-selective ones) [5] Inhibits gastric secretion [5] Procyclidine: NS: Drug-induced parkinsonism, akathisia and acute dystonia; PD; Idiopathic or secondary dystonia
Benzothiophene.. The substituted benzothiophenes are a class of chemical compounds based on benzothiophene. [1] [2] They are closely related to the substituted benzofurans, substituted tryptamines, and to other chemical groups such as the substituted benzodioxoles (or methylenedioxy phenyl compounds).
Solabegron (code name GW-427,353) is a drug which acts as a selective agonist for the β 3 adrenergic receptor.It is being developed for the treatment of overactive bladder and irritable bowel syndrome.
These are used for patients with over-active bladder muscles, who have lost the ability to hold their urine in. [2] Oxybutynin is a common anti-cholinergic medication used to reduce bladder contractions by blocking M3 muscarinic receptors in the detrusor muscle.