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  2. CD4 - Wikipedia

    en.wikipedia.org/wiki/CD4

    CD4 is a co-receptor of the T cell receptor (TCR) and assists the latter in communicating with antigen-presenting cells. The TCR complex and CD4 bind to distinct regions of the antigen-presenting MHC class II molecule. The extracellular D 1 domain of CD4 binds to the β2 region of MHC class II.

  3. pip (package manager) - Wikipedia

    en.wikipedia.org/wiki/Pip_(package_manager)

    Pip's command-line interface allows the install of Python software packages by issuing a command: pip install some-package-name. Users can also remove the package by issuing a command: pip uninstall some-package-name. pip has a feature to manage full lists of packages and corresponding version numbers, possible through a "requirements" file. [14]

  4. Cluster of differentiation - Wikipedia

    en.wikipedia.org/wiki/Cluster_of_differentiation

    The CD nomenclature was proposed and established in the 1st International Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Paris in 1982. [4] [5] This system was intended for the classification of the many monoclonal antibodies (mAbs) generated by different laboratories around the world against epitopes on the surface molecules of leukocytes (white blood cells).

  5. File:CD4+ T cell subsets.pdf - Wikipedia

    en.wikipedia.org/wiki/File:CD4+_T_cell_subsets.pdf

    English: Depiction of the various key subsets of CD4-positive T cells with corresponding associated cytokines and transcription factors. Figure legend T cells leave the thymus in a naïve, antigen non-experiened state. After contact with antigen, T cells may take on one of numerous subsets.

  6. CD4 immunoadhesin - Wikipedia

    en.wikipedia.org/wiki/CD4_immunoadhesin

    CD4 immunoadhesin was first developed in the mid-1990s as a potential therapeutic agent and treatment for HIV/AIDS. The protein is a fusion of the extracellular domain of the CD4 receptor and the Fc domain of human immunoglobulin G (IgG), the most abundant antibody isotype in the human body. [1]

  7. Co-receptor - Wikipedia

    en.wikipedia.org/wiki/Co-receptor

    The CD family of co-receptors are a well-studied group of extracellular receptors found in immunological cells. [4] The CD receptor family typically act as co-receptors, illustrated by the classic example of CD4 acting as a co-receptor to the T cell receptor (TCR) to bind major histocompatibility complex II (MHC-II). [5]

  8. List of human clusters of differentiation - Wikipedia

    en.wikipedia.org/wiki/List_of_human_clusters_of...

    CR3 is a human cell surface receptor, found on polymorphonuclear leukocytes (mostly neutrophils), NK cells, and mononuclear phagocytes like macrophages, which is capable of recognizing and binding to many molecules found on the surfaces of invading bacteria. Binding to the receptor causes phagocytosis and destruction of the foreign cell. CD11c

  9. MHC restriction - Wikipedia

    en.wikipedia.org/wiki/MHC_restriction

    HLA-A projected away from the cell surface and presenting a peptide sequence. The peptide-MHC complex presents a surface that looks like an altered self to the TCR. [11] The surface consisting of two α helices from the MHC and a bound peptide sequence is projected away from the host cell to the T cells, whose TCRs are projected away from the T cells towards the host cells.

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