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  2. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    The general theory of a vaccine intended to "immunize" against drug addiction or other substance abuse is that it would condition the immune system to attack and consume or otherwise disable the molecules of such substances that cause a reaction in the brain, thus preventing the addict from being able to realize the effect of the drug.

  3. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  4. Addiction psychology - Wikipedia

    en.wikipedia.org/wiki/Addiction_psychology

    Addiction affects the brain circuits of reward and motivation, learning and memory, and the inhibitory control over behavior. [24] There are different schools of thought regarding the terms dependence and addiction when referring to drugs and behaviors. One adopted belief is that "drug dependence" equals "addiction."

  5. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    Attempts by government-sponsored drug control policy to interdict drug supply and eliminate drug abuse have been largely unsuccessful. In spite of the huge efforts by the U.S., drug supply and purity has reached an all-time high, with the vast majority of resources spent on interdiction and law enforcement instead of public health .

  6. Addictive behavior - Wikipedia

    en.wikipedia.org/wiki/Addictive_behavior

    Addiction is classified as a chronic brain disorder by the American Society of Addiction Medicine (ASAM). [5] There are several reasons why people develop an addiction. A predisposition to the addictive qualities of substances may be inherited by some people, making it a genetic circumstance. Another cause for addictions could be the environment.

  7. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

  8. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    Chemistry, not moral failing, accounts for the brain’s unwinding. In the laboratories that study drug addiction, researchers have found that the brain becomes conditioned by the repeated dopamine rush caused by heroin. “The brain is not designed to handle it,” said Dr. Ruben Baler, a scientist with the National Institute on Drug Abuse.

  9. Physical dependence - Wikipedia

    en.wikipedia.org/wiki/Physical_dependence

    It is debated whether the entire antipsychotic drug class causes true physical dependency, a subset, or if none do. [38] But, if discontinued too rapidly, it could cause an acute withdrawal syndrome. [39] When talking about illicit drugs rebound withdrawal, especially with stimulants, it is sometimes referred to as "coming down" or "crashing".