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Regeneration in biology is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. [1] Every species is capable of regeneration, from bacteria to humans.
Epimorphosis is defined as the regeneration of a specific part of an organism in a way that involves extensive cell proliferation of somatic stem cells, [1] dedifferentiation, and reformation, [2] as well as blastema formation. [3]
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration , asexual reproduction , metamorphosis , and the growth and differentiation of stem cells in the adult organism.
Universal adaptive strategy theory (UAST) is an evolutionary theory developed by J. Philip Grime in collaboration with Simon Pierce describing the general limits to ecology and evolution based on the trade-off that organisms face when the resources they gain from the environment are allocated between either growth, maintenance or regeneration ...
Nevertheless, this was a huge leap towards whole lung regeneration and transplants for humans, which has already taken another step forward with the lung regeneration of a non-human primate. [ 63 ] Cystic fibrosis is another disease of the lungs, which is highly fatal and genetically linked to a mutation in the CFTR gene .
Compensatory hyperplasia permits tissue and organ regeneration. It is common in epithelial cells of the epidermis and intestine, liver hepatocytes, bone marrow cells, and fibroblasts. It occurs to a lesser extent in bone, cartilage, and smooth muscle cells. Hormonal hyperplasia occurs mainly in organs that depend on estrogen. For example, the ...
The four types of regeneration are epimorphosis, stem cell mediated regeneration, morphallaxis, and compensatory regeneration (compensatory hyperplasia). Epimorphosis occurs when other adult cells in a damaged tissue undergo dedifferentiation and then divide to form an undifferentiated mass of tissue, this new mass encompasses the mass of ...
Some of the earliest ideas and mathematical descriptions on how physical processes and constraints affect biological growth, and hence natural patterns such as the spirals of phyllotaxis, were written by D'Arcy Wentworth Thompson in his 1917 book On Growth and Form [2] [3] [note 1] and Alan Turing in his The Chemical Basis of Morphogenesis (1952). [6]