Search results
Results from the WOW.Com Content Network
LSD is both the prototypical psychedelic and the prototypical lysergamide. As a lysergamide, LSD contains both a tryptamine and phenethylamine group within its structure. As a result of containing a phenethylamine group LSD agonises dopamine receptors as well as serotonin receptors, [ 43 ] making it more energetic in effect in contrast to the ...
LSD, a classical psychedelic, is deemed physiologically safe at standard dosages (50–200 μg) and its primary risks lie in psychological effects rather than physiological harm. [24] [59] A 2010 study by David Nutt ranked LSD as significantly less harmful than alcohol, placing it near the bottom of a list assessing the harm of 20 drugs. [60]
During the 1960s and early 1970s, the drug culture adopted LSD as the psychedelic drug of choice, particularly amongst the hippie community. However, LSD dramatically decreased in popularity in the mid-1970s (see above graph which covers the period 1967– 2008). This decline was due to negative publicity centred on side-effects of LSD use, its ...
The term psychoplastogen comes from the Greek roots psych - (mind), - plast (molded), and - gen (producing) and covers a variety of chemotypes and receptor targets. It was coined by David E. Olson in collaboration with Valentina Popescu, both at the University of California, Davis.
In 1943, Albert Hofmann discovered the hallucinogenic effects of LSD that led to an altered state of consciousness. [5] [6]In 1947, Gion Condrau and Arthur Stoll [5] [7] [8] [9] [6] observed that people diagnosed as "psychotics" had a stronger tolerance for LSD and that the effects of the drug were similar to the symptoms expressed by psychotics themselves.
[9] [10] [11] Perhaps the most significant subjective differences between dissociatives and the classical hallucinogens (such as LSD and mescaline) are the detaching effects, including: depersonalization, the feeling of being unreal, disconnected from one's self, or unable to control one's actions; and derealization, the feeling that the ...
Albert Hofmann (11 January 1906 – 29 April 2008) was a Swiss chemist known for being the first to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD). Hofmann's team also isolated, named and synthesized the principal psychedelic mushroom compounds psilocybin and psilocin . [ 1 ]
The Psychedelic era was the time of social, musical and artistic change influenced by psychedelic drugs, occurring from the mid-1960s [1] to the mid-1970s. [2] The era was defined by the proliferation of LSD and its following influence in the development of psychedelic music and psychedelic film in the Western world.