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Drinking over 1 litre of cola a day might decrease sperm quality by up to 30% [14] (study claims there is a correlation, but not causation) Soy products decrease sperm quality due to the high content of a type of phytoestrogen called isoflavones.
It is unclear if phytoestrogens have any effect on male physiology, with conflicting results about the potential effects of isoflavones originating from soy. [1] Some studies showed that isoflavone supplementation had a positive effect on sperm concentration, count, or motility, and increased ejaculate volume.
Despite the frequent use of isoflavone supplements, there are insufficient data on safety and adverse effects. [1] Isoflavones have GRAS status in the United States. [ 15 ] In a risk assessment of isoflavone supplements for post-menopausal women, the European Food Safety Authority found no adverse effects with intakes up to 150 mg/d, although ...
Put differently, if one person has the average sperm quality and concentration from 50 years ago and another has the average sperm quality and concentration seen today, both of them would be ...
Isoflavonoids and their derivatives are sometimes referred to as phytoestrogens, as many isoflavonoid compounds have biological effects via the estrogen receptor. Medically, isoflavonoids and related compounds have been used in many dietary supplements but the medical and scientific community [who?] is generally skeptical of their use.
Genistein may act as direct antioxidant, similar to many other isoflavones, and thus may alleviate damaging effects of free radicals in tissues. [24] [25] The same molecule of genistein, similar to many other isoflavones, by generation of free radicals poison topoisomerase II, an enzyme important for maintaining DNA stability. [26] [27] [28]
Reproductive toxicants may adversely affect sexual function, ovarian failure, fertility as well as causing developmental toxicity in the offspring. [2] [3] Lowered effective fertility related to reproductive toxicity relates to both male and female effects alike and is reflected in decreased sperm counts, semen quality and ovarian failure.
She also raised questions about the drug's purity and quality after a second dose was given to South Carolina inmate Richard Moore 11 minutes after his execution began in November.