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However, depending on the centrifuge model used, the respective angle of the rotor and the radius may vary, thus the formula gets modified. For example, the Sorvall #SS-34 rotor has a maximum radius of 10.8 cm, so the formula becomes R P M = 299 g r {\textstyle RPM=299{\sqrt {g \over r}}} , which can further simplify to R P M = 91 g {\textstyle ...
In centrifugation the clearing factor or k factor represents the relative pelleting efficiency of a given centrifuge rotor at maximum rotation speed. It can be used to estimate the time t {\displaystyle t} (in hours) required for sedimentation of a fraction with a known sedimentation coefficient s {\displaystyle s} (in svedbergs ):
A centrifuge can be a very effective filter that separates contaminants from the main body of fluid. Industrial scale centrifuges are commonly used in manufacturing and waste processing to sediment suspended solids, or to separate immiscible liquids. An example is the cream separator found in dairies.
Separative work – the amount of separation done by a Uranium enrichment process – is a function of the concentrations of the feedstock, the enriched output, and the depleted tailings; and is expressed in units which are so calculated as to be proportional to the total input (energy / machine operation time) and to the mass processed.
Decanter centrifuges require a centrifugal force for the separation of the solids from the liquid. This characteristic is dependent on the radius of the centrifuge and its angular rotational speed. A decanter centrifuge applies a force equivalent to several thousand G's, which reduces the settling time of the particles.
The sedimentation coefficient is typically dependent on the concentration of the solute (i.e. a macromolecular solute such as a protein). Despite 80+ years of study, there is not yet a consensus on the way to perfectly model this relationship while also taking into account all possible non-ideal terms to account for the diverse possible sizes, shapes, and densities of molecular solutes. [2]
Diagram of a gas centrifuge with countercurrent flow, used for separating isotopes of uranium. A gas centrifuge is a device that performs isotope separation of gases. A centrifuge relies on the principles of centrifugal force accelerating molecules so that particles of different masses are physically separated in a gradient along the radius of a rotating container.
A laboratory ultracentrifuge. In chemistry, a Svedberg unit or svedberg (symbol S, sometimes Sv [a]) is a non-SI metric unit for sedimentation coefficients.The Svedberg unit offers a measure of a particle's size indirectly based on its sedimentation rate under acceleration (i.e. how fast a particle of given size and shape settles out of suspension). [1]