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  2. Avanafil - Wikipedia

    en.wikipedia.org/wiki/Avanafil

    Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 [2] and by EMA on June 21, 2013. [3] Avanafil is sold under the brand names Stendra and Spedra .

  3. Vivus - Wikipedia

    en.wikipedia.org/wiki/Vivus

    Vivus developed an erectile dysfunction drug, Avanafil, that has completed Phase 3 clinical trials. [1] The drug has been approved for use by the FDA, and is sold under the trademark name Stendra. [2] Stendra is the first and only oral ED treatment approved to be taken approximately 15 minutes before sexual activity. [3]

  4. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  5. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    The major PDE5 inhibitors (a subset of the phosphodiesterase inhibitors) are sildenafil, tadalafil, vardenafil, and avanafil, and although all share the same mechanism of action each has unique pharmacokinetic and pharmacodynamic properties which dictate their suitability in various conditions and their side effect profile.

  6. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Avanafil is the only fast-working FDA-tested and approved ED drug, despite the fast-acting male enhancements being pushed these days. When it comes to those herbal or dietary supplements you see ...

  7. Things You Probably Don't Know About Viagra (Like What It Was ...

    www.aol.com/things-probably-dont-know-viagra...

    Other medications for ED, like Cialis (tadalafil), Levitra (vardenafil), and Stendra (avanafil), may also help. Follow the guidance of a medical professional. Always consult a trusted healthcare ...

  8. List of investigational sexual dysfunction drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    BP-101 – undefined mechanism of action (BP 101 - Ovoca Bio - AdisInsight); Bupropion/trazodone (S1P-104, S1P-205, Lorexys, Orexa) – norepinephrine reuptake inhibitor, nicotinic acetylcholine receptor antagonist, 5-HT 2A receptor antagonist, α 1-adrenergic receptor antagonist, weak serotonin reuptake inhibitor (Bupropion/trazodone - AdisInsight)

  9. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.