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When methenamine was first introduced in the late 1800s and early 1900s, doses of 15 to 30 g per day were commonly employed and doses of up to 60 to 180 g per day were tried in some cases. [42] Toxic effects of such high doses included urinary tract and bladder irritation, frequent urination, strangury , and hematuria. [ 42 ]
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Gelatin capsules, informally called gel caps or gelcaps, are composed of gelatin manufactured from the collagen of animal skin or bone. [4] Vegetable capsules, introduced in 1989, [5] are made from cellulose, a structural component in plants. The main ingredient of vegetarian capsules is hydroxypropyl methyl cellulose. In the 21st century ...
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A post-void residual urine greater than 50 ml is a significant amount of urine and increases the potential for recurring urinary tract infections. [ citation needed ] In adults older than 60 years, 50-100 ml of residual urine may remain after each voiding because of the decreased contractility of the detrusor muscle . [ 7 ]
The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...
They are of current medical interest as an antioxidant [164] [165] and for urinary tract ailments. [166] Vaccinium macrocarpon: Cranberry: It was used historically as a vulnerary and for urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems. Modern usage has concentrated on urinary tract related problems. [167] Vaccinium ...
Urination is the release of urine from the bladder to the outside of the body. Urine is released through the urethra and exits the penis or vulva through the urinary meatus in placental mammals, [1] [2]: 38, 364 but is released through the cloaca in other vertebrates.
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