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Guidelines by the American College of Cardiology and the American Heart Association recommend statin treatment for primary prevention of cardiovascular disease in adults with LDL cholesterol ≥ 190 mg/dL (4.9 mmol/L) or those with diabetes, age 40–75 with LDL-C 70–190 mg/dL (1.8–4.9 mmol/dL); or in those with a 10-year risk of developing ...
How statin prescription guidelines have changed. The researchers who conducted the current study explain that the American Heart Association and American College of Cardiology initially developed ...
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. ... on 2013 guidelines from the American Heart ...
Statin-induced hepatotoxicity can cause autoimmune hepatitis and an elevation in serum levels of hepatic enzymes such as alanine aminotransferase, impairing liver function. [20] Myotoxicity is commonly presented with statin-associated muscle symptoms (SAMS), which include myalgia and myositis. [21]
Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. [4]
The recommendations for cholesterol management through lifestyle changes from the National Cholesterol Education Program have evolved over time based on data from epidemiological observations, animal studies, and clinical trials. Animal models have demonstrated a direct relationship between LDL cholesterol and atherosclerosis. Animals consuming ...
Patient Assistance Program guidelines can vary for different medications at the same company, so you’ll want to check for a PAP for every pricey brand-name prescription you take.
The effects of rosuvastatin on low-density lipoprotein (LDL) cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.
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