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The cuneate and gracile nuclei reside at the closed (lower) medulla, so the medial lemniscus is not formed at this level. Fibres from these nuclei will pass to the contralateral side of the brainstem, as the internal arcuate fibres. In the midbrain, it is situated dorsal to the substantia nigra, and medial to either red nucleus. [4]
[7] [8] [9] Nuclei within the MLR receive inputs from the substantia nigra of the basal ganglia and neural centers within the limbic system. [10] Projections from the MLR descend via the medullary and pontine reticulospinal tracts to act on spinal motor neurons supplying the trunk and proximal limb flexors and extensors. [2] [5] [11]
Fornix and septal nuclei; Subcortical areas: Septal nuclei; Amygdala; Nucleus accumbens; Diencephalic structures: Hypothalamus; Mammillary bodies; Anterior nuclei of thalamus; Other areas that have been included in the limbic system include the: Stria medullaris; Central gray and dorsal and ventral nuclei of Gudden
The paramedian pontine reticular formation (PMPRF) is involved in coordinating horizontal conjugate eye movements and saccades. To do so, besides projecting to the ibsilateral abducens nucleus, the PMPRF projects fibers through the MLF to the contralateral oculomotor nucleus (specifically, those of its motor neurons that innervate the medial rectus muscle).
The rostral interstitial nucleus of medial longitudinal fasciculus (riMLF) is a collection of neurons in the medial longitudinal fasciculus in the midbrain. [1] It is responsible for mediating vertical conjugate eye movements (vertical gaze) [1] [2]: 458.e1 and vertical saccades.
Brain anatomy – forebrain, midbrain, hindbrain. The cerebral peduncles each form a lobe ventrally of the tegmentum, on either side of the midline. Beyond the midbrain, between the lobes, is the interpeduncular fossa, which is a cistern filled with cerebrospinal fluid [citation needed]. The majority of each lobe constitutes the cerebral crus.
Section, in the transverse plane through the human midbrain at the level of the superior colliculus, that shows the rough path of each nervus oculomotorius from its nucleus toward the eye and the relative location of the red nucleus. For reference, the bottom of the picture is where the front of the head is located. [citation needed]
Ten of the twelve pairs of cranial nerves either target or are sourced from the brainstem nuclei. [14]: 725 The nuclei of the oculomotor nerve (III) and trochlear nerve (IV) are located in the midbrain. The nuclei of the trigeminal nerve (V), abducens nerve (VI), facial nerve (VII) and vestibulocochlear nerve (VIII) are located in the pons.