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These hormones work in concert with others, such as insulin, peptide YY, and cholecystokinin, to form a complex feedback system that regulates hunger and satiety over both short and long terms. [14] This hormonal symphony provides a much more detailed explanation for hunger regulation than the purely mechanical model proposed by Cannon and ...
Similarly, thirst is the craving for water. [33] A concept of food noise or food chatter has gotten more attention in the early 2020s since the advent of antiobesity indications for a class of medications called GLP1 agonists (such as semaglutide). Food noise is a mental preoccupation with food in general (as opposed to one specific food) that ...
Energy intake is measured by the amount of calories consumed from food and fluids. [1] Energy intake is modulated by hunger, which is primarily regulated by the hypothalamus, [1] and choice, which is determined by the sets of brain structures that are responsible for stimulus control (i.e., operant conditioning and classical conditioning) and cognitive control of eating behavior.
Control centers include the respiratory center and the renin-angiotensin system. An effector is the target acted on, to bring about the change back to the normal state. At the cellular level, effectors include nuclear receptors that bring about changes in gene expression through up-regulation or down-regulation and act in negative feedback ...
A simple negative feedback system is descriptive, for example, of some electronic amplifiers. The feedback is negative if the loop gain AB is negative.. Negative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by ...
A simple negative feedback control system is a cruise control system for a car. A cruise control system has a sensor which "perceives" speed as the rate of spin of the drive shaft directly connected to the wheels. It also has a driver-adjustable 'goal' specifying a particular speed.
The brain is able to overcome negative feedback in these localized systems and continuously evaluate the body's internal set-points. By doing so, the body can regulate its resources and energy storage efficiently. Another key component of allostasis is the brain's perception and subsequent adaptation to chronic stress.
Baroreceptors act immediately as part of a negative feedback system called the baroreflex, [2] as soon as there is a change from the usual mean arterial blood pressure, returning the pressure toward a normal level. These reflexes help regulate short-term blood pressure.