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A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus, and commonly as a mole) [1] [2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells . [ 2 ]
A benign melanocytic nevus is a cutaneous condition characterised by well-circumscribed, pigmented, round or ovoid lesions, generally measuring from 2 to 6 mm in diameter. [1] A benign melanocytic nevus may feature hair or pigmentation as well.
Nevus (pl.: nevi) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. [1] The term originates from nævus , which is Latin for " birthmark "; however, a nevus can be either congenital (present at birth) or acquired.
Congenital melanocytic nevi may be divided into the following types: [6]: 690–1 Small-sized congenital melanocytic nevus is defined as having a diameter less than 2 cm (0.79 in). [6]: 690 Medium-sized congenital melanocytic nevus is defined as having a diameter more than 2 cm (0.79 in) but less than 20 cm (7.9 in). [6]: 690
A pigmented spindle cell nevus is a skin condition characterized by a dark brown to black macule or papule, usually less than 6 mm. [1] It was characterized in 1975. [ 2 ] [ 3 ]
Choroidal nevus (plural: nevi) is a type of eye neoplasm that is classified under choroidal tumors as a type of benign (non-cancerous) melanocytic tumor. [1] A choroidal nevus can be described as an unambiguous pigmented blue or green-gray choroidal lesion, found at the front of the eye, around the iris, [2] or the rear end of the eye.
On histopathology, Spitz nevi characteristically have vertically arranged nests of nevus cells that have both a spindled and an epithelioid morphology. Apoptotic cells may be seen at the dermoepidermal junction. The main histologic differential diagnoses are pigmented spindle cell nevus and malignant melanoma.
The nevus is due to an overgrowth of the epidermis, pigment cells (melanocytes), and hair follicles. [4] This form of nevus was first documented in 1948 by American dermatologist Samuel William Becker (1894–1964).