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Topical antifungal drugs are used to treat fungal infections on the skin, scalp, nails, vagina or inside the mouth. These medications come as creams, gels, lotions, ointments, powders, shampoos, tinctures and sprays. Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus.
The preparation has astringent and antibacterial properties and may be used to treat a number of skin conditions, including insect bites and stings, rashes caused by poison ivy and poison sumac, swelling, allergies, and bruises. However, its main use is for treatment of otitis (ear infection), including otomycosis (fungal ear infection). [2]
An astringent (sometimes called adstringent) is a chemical that shrinks or constricts body tissues. The word derives from the Latin adstringere , which means "to bind fast". Astringency , the dry, puckering or numbing mouthfeel caused by the tannins [ 1 ] [ 2 ] in unripe fruits, lets the fruit mature by deterring eating.
Antipruritics, abirritants, [1] or anti-itch drugs, are medications that inhibit itching (Latin: pruritus).Itching is often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, mites, and contact dermatitis and urticaria caused by plants such as poison ivy (urushiol-induced contact dermatitis ...
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Because fungal skin infections are often accompanied by significant inflammation, this is a desirable property. The fact that butenafine has intrinsic anti inflammatory properties is also desirable since it is not necessary to add topical glucocorticoids , which often come with undesired side effects.
Tolnaftate is included in many products for fungal skin infections such as athlete's foot, jock itch and ringworm. Del Campo says it's best, however, to opt for a preparation designed for nails.
However, hair loss has not been reported with topical selenium disulfide in several large studies. [21] Selenium disulfide should not be applied to damaged skin as there is a risk of systemic absorption and associated toxicity. [1] Systemic symptoms may include tremors, weakness, lethargy, lower abdominal pain, and occasional vomiting. [1]
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