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The drug is bound to albumin with high affinity, while α 1-acid glycoprotein and lipoproteins contribute much less to total plasma protein binding. [7] The unbound or free fraction of levocetirizine has been reported to be 8%. [7] The true volume of distribution of cetirizine is unknown but is estimated to be 0.3 to 0.45 L/kg.
Vyvanse (lisdexamfetamine) – a pro-drug stimulant used to treat attention deficit hyperactivity disorder and binge eating disorder; Vyvanse is converted into Dexedrine in vivo; Viibryd – an antidepressant of the serotonin modulator and stimulators class; Vivactil (protriptyline) an antidepressant also used in the treatment of nerve pain
Levocetirizine was approved for medical use in the United States in 2007, [3] and is available as a generic medication. [4] In 2022, it was the 152nd most commonly prescribed medication in the United States, with more than 3 million prescriptions.
Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.
In some countries, such as Brazil (photo) and France, more than 20% of all drug sales in units are generic. A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire.
Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales. Abbreviations are used in the list as follows: INN = International Nonproprietary Name
A drug that is UA may be sold OTC but only by pharmacists. The drug can be on the shelves like any other product. Examples are domperidone, 400 mg ibuprofen up to 50 tablets and dextromethorphan. A drug that is UAD can also be sold at drugstores which are stores where no prescription can be filled.
The Mercury Drug Corporation, better known as Mercury Drug, is a Filipino pharmacy chain. A subsidiary of the Mercury Group of Companies, it is headquartered in Bagumbayan, Quezon City . [ 5 ] The chain was founded in Santa Cruz, Manila in 1945, [ 1 ] making it the second oldest drugstore chain in the Philippines after Southstar Drug by eight ...