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Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4). [5] [8] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [5] It may also be used to treat and prevent certain types of thyroid tumors. [5] It is not indicated for weight loss. [5]
Replacement occurred faster in the United Kingdom than in North America, but by the 1980s more patients were being prescribed synthetic T4 (levothyroxine) or synthetic T4/T3 combinations than desiccated thyroid extract. [citation needed] Several reasons have been identified as to why prescriptions changed from desiccated thyroid treatment.
Levothyroxine, a drug used to treat hypothyroidism, can lead to reduced bone mass and density in older adults with normal thyroid levels, a small cohort study has shown.
In people with central/secondary hypothyroidism, TSH is not a reliable marker of hormone replacement and decisions are based mainly on the free T 4 level. [8] [10] Levothyroxine is best taken 30–60 minutes before breakfast, or four hours after food, [8] as certain substances such as food and calcium can inhibit the absorption of levothyroxine ...
The thyroid gland is covered by a thin fibrous capsule, [4] which has an inner and an outer layer. The inner layer extrudes into the gland and forms the septa that divide the thyroid tissue into microscopic lobules. [4]
Medicare Part D is an add-on that can help cover the costs of prescription medications not covered by Original Medicare. These include: certain oral chemotherapy medications.
For patients taking levothyroxine, TSH may be boosted by discontinuing levothyroxine for 3–6 weeks. [6] This long period of hormone withdrawal is required because of levothyroxine's relatively long biological half-life, and may result in symptoms of hypothyroidism in the patient. The shorter half-life of liothyronine permits a withdrawal ...
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