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Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
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From the list above, relationship issues seem to have the most impact on performance anxiety. ... PDE5 inhibitors work by inhibiting the PDE5 enzyme, causing blood vessels near the privates to ...
Phosphodiesterase-5. A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).
Cyclic guanosine monophosphate-specific phosphodiesterase type 5 is an enzyme (EC 3.1.4.17) from the phosphodiesterase class. It is found in various tissues, most prominently the corpus cavernosum of the clitoris and of the penis as well as the retina. [5] It has also been recently discovered to play a vital role in the cardiovascular system.
These all belong to a class of medications referred to as PDE5 inhibitors. They work by increasing blood flow to your privates, making it easier to get and stay hard when you feel aroused.
If you have dysfunction problems like ED, prescription medication may be a good option to increase stamina. PDE5 inhibitors are ED drugs that can help you get aroused by increasing blood flow to ...