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Just like blood testing, saliva testing detects the presence of parent drugs and not their inactive metabolites. This results in a shorter window of detection for cannabis by saliva testing. [23] Delta 9 THC is the parent compound. If a saliva sample is tested in a lab, the detection level can be as low as 0.5 ng/mL (up to 72 hours after intake ...
The THC molecule, and related compounds, are usually detectable in drug tests from 3 days up to 10 days. [citation needed] Long-term users can produce positive tests for two to three months after ceasing cannabis use (see drug test). [17]
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [68] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
Any use of marijuana could raise the risk of heart attack and stroke, even in people who don’t use cigarettes or don’t have existing heart disease, a new study finds.
Blood THC levels typically peak quickly after smoking cannabis, reaching upward of 100 nanograms per milliliter of blood within 15 minutes of smoking it. Then, THC levels drop rapidly to less than ...
THC and its 11-OH-THC and THC-COOH metabolites can be detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of immunoassay and chromatographic techniques as part of a drug use testing program or in a forensic investigation. [58] [59] [60] There is ongoing research to create devices capable of detecting THC in ...
A 2022 study published in the Journal of Psychopharmacology found that participants given oral cannabis (the lab-grade alternative to an edible) showed low blood THC concentration at the height of ...
[64] 11-OH-THC is the first metabolic product in this pathway. Both Delta-9-THC and 11-OH-THC are psychoactive. The metabolism of THC into 11-OH-THC plays a part in the heightened psychoactive effects of edible cannabis. [65] Next, 11-OH-THC is metabolized in the liver into 11-COOH-THC, which is the second metabolic product of THC.