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2. HAS1 - Wikipedia

   en.wikipedia.org/wiki/HAS1

   HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase. [6]

3. Hyaluronan synthase - Wikipedia

   en.wikipedia.org/wiki/Hyaluronan_synthase

   There are three mammalian hyaluronan synthases described to date - HAS1, HAS2, and HAS3. Each of these isoforms resides at a different chromosome location [ 2 ] and has been cloned . [ 3 ] Two of the main differences between the isoforms are the chain length of the hyaluronan molecules that they produce and the ease with which they can be ...

4. Hyaluronic acid - Wikipedia

   en.wikipedia.org/wiki/Hyaluronic_acid

   Hyaluronic acid is synthesized by a class of integral membrane proteins called hyaluronan synthases, of which vertebrates have three types: HAS1, HAS2, and HAS3. These enzymes lengthen hyaluronan by repeatedly adding D -glucuronic acid and N -acetyl- D -glucosamine to the nascent polysaccharide as it is extruded via ABC-transporter through the ...

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6. Glycosaminoglycan - Wikipedia

   en.wikipedia.org/wiki/Glycosaminoglycan

   Hyaluronan (-4GlcUAβ1-3GlcNAcβ1-) n. The fourth class of GAG, hyaluronic acid (HA), is not sulfated and is synthesized by three transmembrane synthase proteins HAS1, HAS2, and HAS3. HA, a linear polysaccharide, is composed of repeating disaccharide units of →4)GlcAβ(1→3)GlcNAcβ(1→ and has a very high molecular mass, ranging from 10 5 ...

7. Microbial hyaluronic acid production - Wikipedia

   en.wikipedia.org/wiki/Microbial_hyaluronic_acid...

   Hyaluronan synthase, that is a membrane-binding enzyme, is one of the factors that reduces the production of HA. Hyaluronan synthase limits hyaluronic acid production by affecting cell morphology. Hyaluronan synthase limits hyaluronic acid production by affecting cell morphology.