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Part of the power of statins lies in the fact that they cause few side effects. “Generally, about 90 out of 100 people have no trouble with a stain,” says Dr. Blumenthal.
A new analysis re-evaluates statins and who should use them. Statins are widely used to help lower cholesterol. Using a new analysis, researchers found that millions of people may be taking ...
Off-label abuse. [3] Methapyrilene: 1979 Germany, UK, US Animal carcinogenicity. [3] Methaqualone: 1984 South Africa (1971), India (1984), United Nations (1971–1988) Withdrawn because of risk of addiction and overdose [33] [34] Metipranolol: 1990 UK, others Uveitis. [3] Metofoline: 1965 US Unspecific experimental toxicity. [3] Mibefradil: 1998
Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself. [1] [2] When initiated by the clinician, it is known as deprescribing. [3]
High cholesterol can be treated with a class of medications called statins that work by reducing the levels of cholesterol made by the liver and by helping to remove cholesterol that’s already ...
In studies using standard doses, statins have been found to lower LDL-C by 18% to 55%, depending on the specific statin being used. A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after ...
On average, statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment. [37] A greater benefit is observed with high-intensity statin therapy. [38]
The body needs cholesterol to build cells and make vitamins and certain hormones, but too much of it can cause fat to collect in arteries, increasing the risk of heart attack and stroke.