Search results
Results from the WOW.Com Content Network
CA-125 was initially detected using the murine monoclonal antibody designated OC125. Robert Bast , Robert Knapp and their research team first isolated this monoclonal antibody in 1981. [ 28 ] The protein was named "cancer antigen 125" because OC125 was the 125th antibody produced against the ovarian cancer cell line that was being studied.
CA-125 levels appear to fall during endometriosis treatment, but it has not shown a correlation with disease response. [ 121 ] Another review in 2011 identified several putative biomarkers upon biopsy, including findings of small sensory nerve fibers or defectively expressed β3 integrin subunit. [ 123 ]
Simufilam (PTI-125) is an experimental medication for the treatment of Alzheimer's disease. [ 2 ] [ 3 ] It was being developed by the American pharmaceutical firm Cassava Sciences . Development of simufilam was discontinued in November 2024 after it failed to show clinical benefit during phase III clinical trials .
113 - 125 3 Diseases and Disorders of the Ear, Nose, Mouth And Throat 129 - 159 4 Diseases and Disorders of the Respiratory System 163 - 208 5 Diseases and Disorders of the Circulatory System 215 - 316 6 Diseases and Disorders of the Digestive System 326 - 395 7 Diseases and Disorders of the Hepatobiliary System And Pancreas 405 - 446 8
Increased gastrin secretion also leads to peptic ulcers in > 50% of MEN 1 patients. Usually the ulcers are multiple or atypical in location, and often bleed, perforate, or become obstructed. Peptic ulcer disease may be intractable and complicated. Among patients presenting with Zollinger-Ellison syndrome, 20 to 60% have MEN 1.
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Iodine-125 (125 I) is a radioisotope of iodine which has uses in biological assays, nuclear medicine imaging and in radiation therapy as brachytherapy to treat a number of conditions, including prostate cancer, uveal melanomas, and brain tumors. It is the second longest-lived radioisotope of iodine, after iodine-129.
Prostate cancer screening is the screening process used to detect undiagnosed prostate cancer in men without signs or symptoms. [1] [2] When abnormal prostate tissue or cancer is found early, it may be easier to treat and cure, but it is unclear if early detection reduces mortality rates. [2] Screening precedes a diagnosis and subsequent treatment.