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Phocomelia is a congenital condition that involves malformations of human arms and legs which result in a flipper-like appendage. [1] [2] A prominent cause of phocomelia is the mother being prescribed the use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined. [2]
Crush injury is compression of the arms, legs, or other parts of the body that causes muscle swelling and/or neurological disturbances in the affected areas of the body, while crush syndrome is a localized crush injury with systemic manifestations. [1]
The exact cause of lipodermatosclerosis is unknown. [3] [6] Venous disease, such as venous incompetence, venous hypertension, and body mass may be relevant to the underlying pathogenesis. [3] Increased blood pressure in the veins (venous hypertension) can cause diffusion of substances, including fibrin, out of capillaries.
[26] [26] Examples include a severe crush injury or an open or closed fracture of an extremity. [26] Rarely, ACS can develop after a minor injury or another medical issue. [12] It can also affect the thigh, buttock, hand, abdomen, and foot. [19] [14] The most common cause of acute compartment syndrome is a fractured bone, usually the tibia.
Marfan syndrome is named after Antoine Marfan, [11] the French pediatrician who first described the condition in 1896 after noticing striking features in a five-year-old girl. [ 12 ] [ 77 ] The gene linked to the disease was first identified by Francesco Ramirez at the Mount Sinai Medical Center in New York City in 1991.
Up to 11% of women [2] Lipedema is a condition that is almost exclusively found in women [ 3 ] and results in enlargement of both legs due to deposits of fat under the skin. [ 2 ] Women of any weight may be affected [ 2 ] [ 3 ] and the fat is resistant to traditional weight-loss methods. [ 4 ]
Jade Collett, then 22, noticed her foot was turning outwards during a night of drinking with pals, but initially dismissed the symptoms a "twinged nerve" When her foot continued to hurt, she ...
Myotonia congenita is a congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder.The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles and rigidity. [1]