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The effects of carfentanil, including overdose, can be reversed by the opioid antagonists naloxone and naltrexone, though higher doses than usual may be necessary compared to other opioids. [1] [2] [3]: 23 Carfentanil is a structural analogue of the synthetic opioid analgesic fentanyl. [4]
An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. [3] [5] This preventable pathology can be fatal if it leads to respiratory depression, a lethal condition that can cause hypoxia from slow and shallow breathing. [3]
Assuming that these were the only active constituents (which has not been verified by the Russian military), the primary acute toxic effect to the theatre victims would have been opioid-induced apnea; in this case mechanical ventilation and/or treatment with naloxone, the specific antidote for poisoning with carfentanil in humans, would have ...
(The Center Square) – The federal government reported a sharp increase in overdose deaths due to carfentanil, a powerful opioid 100 times stronger than fentanyl that veterinarians use on bears ...
The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug or other substances may lead to severe psychological or physical dependence. The complete list of Schedule II substances is as follows.
The Oregon Health Authority plans to offer free opioid overdose reversal kits to middle and high schools throughout the state, the agency said Tuesday.
Dr. Jesse Davis, of the Lummi Healing Spirit opioid treatment program, talks with nurse manager Edna Revey, right, at the program's seven-bed facility on the Lummi Reservation.
Reversing a gray death overdose may require multiple doses of naloxone. By contrast, an overdose from morphine or from high-purity heroin would ordinarily need only one dose. [ 5 ] This difficulty is regularly encountered when treating overdoses of high-affinity opioids in the fentanyl chemical family or with buprenorphine .