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Common side effects include abdominal pain, headache, nausea, and weight loss. [2] There are concerns from animal studies that it may increase the risk of cancer but these concerns have not been found in human trials. [5] Nifurtimox is not recommended in pregnancy or in those with significant kidney or liver problems. [5] It is a type of ...
Structures with names 4- and 5-nitroimidazole are equivalent from the perspective of drugs since these tautomers readily interconvert. Drugs of the 5-nitro variety include metronidazole, tinidazole, nimorazole, dimetridazole, pretomanid, ornidazole, megazol, and azanidazole. Drugs based on 2-nitroimidazoles include benznidazole and azomycin. [3]
The most common side effects of nitrofurantoin are nausea, headache, and flatulence. Less common adverse events (occurring in less than 1% of those taking the drug) include: [9] Gastrointestinal: diarrhea, dyspepsia, abdominal pain, constipation, emesis; Neurologic: dizziness, drowsiness, amblyopia; Respiratory: acute pulmonary hypersensitivity ...
It is on the World Health Organization's List of Essential Medicines. [4] It often comes as a 50/50 mixture with oxygen. [1] Devices with a demand valve are available for self-administration. [5] The setup and maintenance is relatively expensive for developing countries. [6] [7] There are few side effects, other than vomiting, with short-term use.
Nitroglycerin was written about as early as 1846 [5] [6] and came into medical use in 1878. [7] [8] [9] The drug nitroglycerin is a dilute form of the same chemical used as the explosive, nitroglycerin. [9] Dilution makes it non-explosive. [9]
[1] [38] Although he was aware of DNP's narrow therapeutic index, Tainter tried the drugs on obese patients and published successful results in 1933; average weight loss was 20 pounds (9.1 kg) and most recipients did not report adverse effects. In 1934, Tainter estimated that at least 100,000 people had been treated with DNP in the United ...
Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure. [3] This may be done if the blood pressure is very high and resulting in symptoms, in certain types of heart failure, and during surgery to decrease bleeding. [3]
The Dutch, British and French system called the System of Objectified Judgement Analysis for assessing whether drugs should be included in drug formularies based on clinical efficacy, adverse effects, pharmacokinetic properties, toxicity, and drug interactions was used to assess nitrazepam. A Dutch analysis using the system found nitrazepam to ...