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  2. FDA panel flags insufficient data for Merck's chronic cough drug

    www.aol.com/news/us-fda-panel-votes-against...

    The U.S. Food and Drug Administration's (FDA) panel voted 12 to 1 against the late-stage data submitted by Merck for the drug gefapixant, which showed a small reduction in cough frequency compared ...

  3. US FDA declines to approve Merck's chronic cough drug - AOL

    www.aol.com/news/us-fda-declines-approve-mercks...

    The FDA's decision gives some breathing room to rival GSK's chronic cough treatment camlipixant, which is in late-stage development with anticipated regulatory approval and launch in 2026 ...

  4. US FDA staff flags concerns on Merck's chronic cough drug - AOL

    www.aol.com/news/us-fda-staff-flags-concerns...

    The panel will deliberate whether the data provided by Merck establishes that a small reduction in cough frequency with the use of gefapixant is clinically meaningful to patients. US FDA staff ...

  5. Camlipixant - Wikipedia

    en.wikipedia.org/wiki/Camlipixant

    Camlipixant is an investigational new drug that is being evaluated for the treatment of chronic cough. [1] It is a P2X3 receptor antagonist. [2] See also. gefapixant;

  6. Gefapixant - Wikipedia

    en.wikipedia.org/wiki/Gefapixant

    Gefapixant, sold under the brand name Lyfnua, is a medication used to treat chronic (long-term) cough. [1] It acts as an antagonist of the P2RX3 receptor. [2] [3] [4]

  7. Guaifenesin/codeine - Wikipedia

    en.wikipedia.org/wiki/Guaifenesin/codeine

    Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1]

  8. Benzonatate - Wikipedia

    en.wikipedia.org/wiki/Benzonatate

    Benzonatate is a prescription non-opioid alternative for the symptomatic relief of cough.[7] [9] It has been found to improve cough associated with a variety of respiratory conditions including asthma, bronchitis, pneumonia, tuberculosis, pneumothorax, opioid-resistant cough in lung cancer, and emphysema.

  9. Adenosine receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Adenosine_receptor_antagonist

    An adenosine receptor antagonist is a drug which acts as an antagonist of one or more of the adenosine receptors. [1] The best known are xanthines and their derivatives (natural: caffeine, [2] theophylline, [3] and theobromine; and synthetic: PSB-1901 [4]), but there are also non-xanthine representatives (e.g. ISAM-140, [5] ISAM-R316, [6] etrumadenant, [7] and AZD-4635 [8])