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Losartan is excreted in the urine, and in the feces via bile, as unchanged drug and metabolites. [44] About 4% of an oral dose is excreted unchanged in urine, and about 6% is excreted in urine as the active metabolite. [44] The terminal elimination half-lives of losartan and EXP3174 are about 1.5 to 2.5 hours and 3 to 9 hours, respectively. [44]
Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [1] [2] It consists of losartan, an angiotensin II receptor blocker; and hydrochlorothiazide, a thiazide diuretic. [1] [2] It is taken by mouth. [1] [2]
Dizziness is a common medical complaint, affecting 20–30% of persons. [4] Dizziness is broken down into four main subtypes: vertigo (~25–50%), disequilibrium (less than ~15%), presyncope (less than ~15%), and nonspecific dizziness (~10%). [5] Vertigo is the sensation of spinning or having one's surroundings spin about them. Many people find ...
What causes vertigo and dizziness? “Dizziness is generally a more neurological cause or a potential cardiac cause. For example, it could be a blood flow issue or stenosis of a carotid artery ...
Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...
Gout may be worsened by thiazide diuretics, while losartan reduces serum urate. [64] Kidney stones may be improved with the use of thiazide-type diuretics [65] Heart block. β-blockers and nondihydropyridine calcium channel blockers should not be used in patients with heart block greater than first degree. JNC8 does not recommend β-blockers as ...
Heavy-headedness is the feeling of faintness, dizziness, or feeling of floating, wooziness. [1] [2] [3] Individuals may feel as though their head is heavy; also feel as though the room is moving/spinning also known as vertigo. Some causes of heavy-headedness can be tough to get rid of and can last a long period of time, however most can be treated.
Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [1] [2] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.