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Appearance of the inside of the colon showing one invasive colorectal carcinoma (the crater-like, reddish, irregularly shaped tumor) Gross appearance of a colectomy specimen containing two adenomatous polyps (the brownish oval tumors above the labels, attached to the normal beige lining by a stalk) and one invasive colorectal carcinoma (the ...
A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. [1] [2] This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC ...
The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma ( colon cancer ). [ 1 ] [ 2 ] [ 3 ] They often manifest as colorectal polyps .
Gross pathology, serosal view, of small intestine with adenocarcinoma, showing cancer with infiltrative growth, causing stenosis. Luminal view, showing the stenotic infiltrative growth across the entire intestinal wall.
Description: Another case of villous adenoma of the transverse colon, this one more discrete and polyp-like than the case above. Although it had a semi-decent stalk, it was still far too large for safe removal by endoscopy, so the surgeon was called in to do a segmental resection of the colon.
Signet ring cell, as seen in a case of colon adenocarcinoma with mucinous features, showing a tumor cell with a vacuole of mucin. H&E stain. Signet ring for comparison. In histology, a signet ring cell is a cell with a large vacuole. The malignant type is seen predominantly in carcinomas.
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The adenoma, lacking the "carcinoma" attached to the end of it, suggests that it is a benign version of the malignant adenocarcinoma. The gastroenterologist uses a colonoscopy to find and remove these adenomas and polyps to prevent them from continuing to acquire genetic changes that will lead to an invasive adenocarcinoma.