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This is a list of miscellaneous agonists of the serotonin receptor subtype 5-HT 2A (and other 5-HT 2 subtypes to a varying extent) ...
Lisuride – an antiparkinson dopamine agonist of the ergoline class, that is also a dual 5-HT 2A / 5-HT 2C agonist [69] and 5-HT 2B antagonist. [ 70 ] Mefloquine – an antimalarial drug, also produces psychiatric side effects which may be mediated through 5-HT 2A and/or 5-HT 2C receptors.
Agonists of the 5-HT2A receptor. Subcategories. This category has the following 3 subcategories, out of 3 total. ... Psychedelic drug; Q. Quipazine; T. TCB-2; Tryptamine
These partial agonists have proven relatively safe after having seen widespread abuse by drug users for many decades. [11] Activation of the 5-HT 2A receptor is also implicated in serotonin syndrome caused by indirect serotonin receptor agonists like serotonin reuptake inhibitors, serotonin releasing agents, and monoamine oxidase inhibitors.
The 5-HT 1B receptor as an example of a metabotropic serotonin receptor. Its crystallographic structure in ribbon representation. 5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.
Vabicaserin is a full agonist with approximately 4-fold greater selectivity for 5-HT 2C over these related receptors, in terms of binding affinity. Vabicacserin is a full agonist in stimulating the 5-HT 2C receptor; it was discovered when a class of tetrahydroquinoline-fused diazepines were being researched as possible potent 5-HT 2C receptor ...
Non-hallucinogenic serotonin 5-HT 2A receptor agonists, either due to being biased agonists, partial agonists, or peripherally selective. Some of these agents may be weakly hallucinogenic or hallucinogenic only at very high doses rather than fully non-hallucinogenic.
15550 Ensembl ENSG00000178394 ENSMUSG00000021721 UniProt P08908 Q64264 RefSeq (mRNA) NM_000524 NM_008308 RefSeq (protein) NP_000515 NP_032334 Location (UCSC) Chr 5: 63.96 – 63.96 Mb Chr 13: 105.58 – 105.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The serotonin 1A receptor (or 5-HT 1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin ...